Heterocyclic compounds, their production and use as tachykinin reactor antagonists

摘要

A novel compound represented by the formula: <IMAGE> wherein Ring A and Ring B respectively stands for an optionally substituted homo- or hetero-cyclic ring, and at least one of them stands for an optionally substituted heterocyclic ring stand; Ring C stands for an optionally substituted benzene ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue; one of X and Y stands for -NR1- (R1 stands for a hydrogen atom or an optionally substituted hydrocarbon residue) or -O-, and the other stands for-CO- or -CS-, or one of them stands for -N= and the other stands for =CR2- (R2 stands for a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon residue, an optionally substituted amino group or an optionally substituted hydroxyl group); n denotes 1 or 2 or salts thereof which have an excellent tachykinin receptor antagonistic action and inhibitory action on plasma extravasation.