发明名称 Method for increasing blood-ocular barrier permeability with permeabilizer peptides
摘要 The permeability of the blood-ocular barrier to therapeutic or diagnostic agents in the bloodstream of a host is increased by administering a permeabilizer peptide, preferably bradykinin or a bradykinin analogue, into the bloodstream of a host. The invention provides methods of treatment or diagnosis of ocular diseases by administration of a permeabilizer peptide, such as permeabilizer A-7, in combination with a therapeutic or diagnostic agent.
申请公布号 US5585355(A) 申请公布日期 1996.12.17
申请号 US19940306873 申请日期 1994.09.12
申请人 ALKERMES, INC. 发明人 GRANEY, WILLIAM F.
分类号 A61K38/00;A61K38/04;A61K45/00;A61K49/00;A61P9/08;A61P27/02;A61P31/12;A61P43/00;(IPC1-7):A61K38/00;C07K5/00;C07K7/00 主分类号 A61K38/00
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