| 摘要 |
PCT No. PCT/EP96/02254 Sec. 371 Date Mar. 14, 1997 Sec. 102(e) Date Mar. 14, 1997 PCT Filed May 24, 1996 PCT Pub. No. WO96/37498 PCT Pub. Date Nov. 28, 1996The present invention relates to new 5H-thiazolo[3,2-a]pyrimidin -5-one derivatives having the formula (I): <IMAGE> (I) wherein Ar is phenyl optionally substituted by one or two groups selected from halogen, alkyl having from 1 to 4 carbon atoms, methylendioxy, alkoxy having from 1 to 4 carbon atoms, and trifluoromethyl; and R is a group selected from (a) or (b): <IMAGE> (a) <IMAGE> (b) as well as their pharmaceutically acceptable addition salts, which are useful in the treatment of psychosis, schizophrenia and anxiety. This invention also discloses methods and intermediates for their preparation and pharmaceutical compositions containing them. |
