发明名称 Cyclic peptides antifungal agents
摘要 Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I <CHEM> where: R', R", R"', R<x1>, R<x2>, R<y1>, R<y2>, R<y3> R<y4>, and R<0> are as defined hereinabove; and R<2> is <CHEM> or <CHEM> R<3> is <CHEM> or <CHEM> R<3a> is C1-C6 alkyl or C1-C6 alkoxy; R<3b> and R<3c> are independently phenyl or naphthyl; R<3d> is C1-C12 alkyl, C1-C12 alkoxy or -O-(CH2)m-ÄO-(CH2)nÜp-O-(C1-C12 alkyl); m is 2, 3 or 4; n is 2, 3 or 4; p is 0 or 1; or a pharmaceutically acceptable salt thereof.i
申请公布号 AU5799396(A) 申请公布日期 1996.12.11
申请号 AU19960057993 申请日期 1996.05.20
申请人 ELI LILLY AND COMPANY 发明人 LISA M. H. LAGRANDEUR;MICHAEL J RODRIGUEZ;MARK J. ZWEIFEL
分类号 A61K38/00;A61P31/04;A61P31/10;A61P33/00;C07K1/113;C07K7/56 主分类号 A61K38/00
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