发明名称 |
ANTI-IDIOTYPE ANTIBODY INDUCING IMMUNE RESPONSE AGAINST EPITHELIAL CELL PROPAGATION FACTOR ACCEPTOR |
摘要 |
The present invention relates to anti-idiotypic antibodies which induce an immune response against tumors, bearing as antigen the epidermal growth factor receptor (EGFR). The antibodies of the invention may mimic said antigen. As preferred embodiment the antibodies of the invention derive from mAB 425 (ATCC HB 9629) or a humanized or chimeric derivative thereof. |
申请公布号 |
JPH08325299(A) |
申请公布日期 |
1996.12.10 |
申请号 |
JP19960151798 |
申请日期 |
1996.05.24 |
申请人 |
MERCK PATENT GMBH |
发明人 |
ANA KARUCHIEREERU;ERIZABEETO ROSERU;ARISHIA GOMESU;HAIME ADAN;HAIME PIURATSUTSU |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P35/00;C07K14/705;C07K16/00;C07K16/42;C12N15/02;C12P21/08;C12R1/91;(IPC1-7):C07K16/42 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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