发明名称 (ARYL OR HETEROAROMATIC METHYL)-2,2'-BI-1H-IMIDAZOLES
摘要 This invention relates to novel (aryl or heteroaromatic methyl)-2,2'-1H-biimidazoles; to a process for their production comprising of reacting an appropriate alpha-brominated or alpha-chlorinated, substituted or nonsubstituted, methylated monoaromatic ring compound with 2,2'-bi-1H-imidazole in a solvent such as ethanol in the presence of a base such as sodium hydroxide under reflux conditions; and to pharmaceutical compositions and methods of treating hypertension with such compounds.
申请公布号 CA1338786(C) 申请公布日期 1996.12.10
申请号 CA19880572886 申请日期 1988.07.22
申请人 MERRELL DOW PHARMACEUTICALS (CANADA) INC. 发明人 MATTHEWS, DONALD P.;WHITTEN, JEFFREY P.;MCCARTHY, JAMES R.
分类号 A61K31/415;A61K31/425;A61P9/12;C07D233/54;C07D233/60;C07D233/64;C07D405/06;C07D405/14;C07D409/06;C07D409/14;C07D417/14;(IPC1-7):C07D403/04 主分类号 A61K31/415
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