发明名称 |
Methods for diagnosis of peripheral nerve damage |
摘要 |
Methods of diagnosing peripheral nerve damage, including diagnosing and monitoring chronic back and cervical pain are disclosed. The methods involve subjecting a body fluid sample from a patient suspected of having chronic lumbar or cervical pain and peripheral nerve damage to two-dimensional electrophoresis or an immunoassay and measuring relative amounts of protein or proteins which increase or decrease in concentration as compared to a standard control. A preferred method employs an Apo-E variant as a marker of peripheral nerve damage. Also disclosed are kits for use with the diagnostic methods.
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申请公布号 |
US5583201(A) |
申请公布日期 |
1996.12.10 |
申请号 |
US19940242980 |
申请日期 |
1994.05.16 |
申请人 |
MONOCLONETICS INTERNATIONAL, INC.;UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
CAMERON, SR., BRUCE M.;MERRIL, CARL R.;CREED, GUY J.;VANDERPUTTEN, DALE |
分类号 |
A61K39/395;C07K16/18;C12N15/02;C12P21/08;C12R1/91;G01N27/447;G01N33/50;G01N33/53;G01N33/561;G01N33/577;G01N33/68;(IPC1-7):C07K14/435;C07K1/14;A61K38/17;C12Q1/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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