CLONING AND EXPRESSION OF DNA INVOLVED IN THE BIOSYNTHESIS OF CYCLOPROPANATED MYCOLIC ACIDS IN MYCOBACTERIUM TUBERCULOSIS

摘要

DNA and protein compositions useful for both diagnosis and design of therapeutics for treatment of tuberculosis and other mycobacterial infections. More specifically, the present invention relates to DNA and protein compositions which are responsible for the cyclopropanation of mycolic acids in M. tuberculosis and other pathogenic forms of mycobacterium.