| 摘要 |
There is disclosed a stable pharmaceutical solid composition comprising enalapril as the sodium salt, which is made by the steps of: i) mixing enalapril maleate with a carrier, an alkaline sodium compound, and water ii) drying the wet mass, and; iii) further processing the resultant dried mass into tablets. When the water is added in the aforesaid process, an acid-base reaction occurs which converts the enalapril maleate into the more stable enalapril sodium salt.
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