发明名称 FUSED POLYCYCLIC HETEROCYCLE DERIVATIVES
摘要 <p>Novel fused polycyclic heterocycle derivatives represented by general formula (I) or pharmacologically acceptable salts thereof which have an excellent antitumor effect, and a process for producing the same, wherein the ring A represents an optionally substituted monocyclic aromatic ring or a fused bicyclic ring wherein at least one of the rings is an aromatic ring; the ring B represents pyrrole, 4H-1,4-dioxane, 4H-1,4-thiazine or 4(1H)-pyridone; the ring C represents an optionally substituted monocyclic or fused bicyclic aromatic ring; and Y represents -e-f (wherein e represents lower alkylene; and f represents amidino, guanidino, or amino optionally substituted by hydroxy or lower alkyl optionally lower-alkylaminated); excluding a combination wherein the rings A and C are each an optionally substituted monocyclic aromatic ring.</p>
申请公布号 WO9638446(A1) 申请公布日期 1996.12.05
申请号 WO1996JP01487 申请日期 1996.05.31
申请人 EISAI CO., LTD.;SUGUMI, HIROYUKI;NIIJIMA, JUN;KOTAKE, YOSHIHIKO;OKADA, TOSHIMI;KAMATA, JUN-ICHI;YOSHIMATSU, KENTARO;NAGASU, TAKESHI;NAKAMURA, KATSUJI;UENAKA, TOSHIMITSU;YAMAGUCHI, ATSUMI;YOSHINO, HIROSHI;KOYANAGI, NOZOMU;KITO, KYOSUKE 发明人 SUGUMI, HIROYUKI;NIIJIMA, JUN;KOTAKE, YOSHIHIKO;OKADA, TOSHIMI;KAMATA, JUN-ICHI;YOSHIMATSU, KENTARO;NAGASU, TAKESHI;NAKAMURA, KATSUJI;UENAKA, TOSHIMITSU;YAMAGUCHI, ATSUMI;YOSHINO, HIROSHI;KOYANAGI, NOZOMU;KITO, KYOSUKE
分类号 A61K31/522;A61K31/542;A61K31/585;A61P35/00;C07D209/90;C07D215/00;C07D239/00;C07D265/34;C07D279/14;C07D311/00;C07D317/00;C07D471/06;C07D471/16;C07D487/06;C07D487/16;C07D491/16;C07D495/16;C07D498/06;C07D498/16;C07D513/06;(IPC1-7):C07D471/06;A61K31/495;A61K31/535;A61K31/54 主分类号 A61K31/522
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