| 摘要 |
<p>A method of the diagnosis of insulin dependent diabetes melitus with the use of a protein having the following characteristics, a peptide or a protein having a fragment of this protein, etc. so as to confirm the presence of the islet cell antibody (ICA) in a specimen from a subject at a high sensitivity and a high reproducibility, thus diagnosing insulin dependent diabetes melitus at a high accuracy: (1) molecular weight: 15 kD determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis; (2) isoelectric point: pI = 5.5; (3) amino acid sequence from the N-terminus to the 15th residue, according to formula (I).</p> |
