Process for making 1,3-propanediol from carbohydrates using mixed microbial cultures

摘要

The present invention provides a process for the biotransformation of a carbohydrate carbon source to 1,3-propanediol using mixed yeast and bacterial cultures wherein the carbohydrate is first fermented to glycerol by the yeast cell and then converted to 1,3-propanediol by the bacterial cell containing an active diol or glycerol dehydratase enzyme in this process both the yeast and bacterial cultures are supported on the same carbon source, and 1,3-propanediol is isolated from the media.