| 摘要 |
FIELD: organic chemistry. SUBSTANCE: product: compound of the formula (I)where Rand R- alkyl-group involving from 1 to 8 carbon atoms, or benzyl-group, or they form together with nitrogen atom with which they are bound the saturated heterocycle with 5 or 6 atoms; Ris methyl-group at position α or b; n = 2-10, or Rand Rform together oxo-group, or R- hydrogen atom, hydroxyl or alkyloxyl-group involving 12 carbon atoms (not above), and R- hydrogen atom, hydroxyl, acyloxyl-group involving 12 carbon atoms (not above), alkyl, alkylene or alkynyl-group each of that involves 8 carbon atoms (not above); Rand Rform together oxo-group or, similar or different, mean hydrogen atom, hydroxyl or acyloxyl-group, or Rand Rform together double bond, and Rand R- hydrogen atom, and also their salts with pharmaceutically acceptable acids. Synthesized compounds were used for fertility control, in part, male fertility control. EFFECT: improved method of synthesis. |
