| 摘要 |
FIELD: biotechnology. SUBSTANCE: plasma or serum of donor blood is treated with chloroform, supernatant is precipitated with polyethylene glycol-6000 aqueous solution, followed by ion-exchange and metal-chelate chromatography, dialysis and sterilizing filtration. Invention ensures to obtain complex of leukocyte proteinase inhibitors simultaneously - α-macroglobulin, α-antichymotrypsin and α-proteinase inhibitor of antitrypsin. Method can be used for biosynthesis of interferon and its purification. EFFECT: improved method of inhibitors preparing. |
