发明名称 |
Identification and characterization of inhibtors of protein farnesyltransferase |
摘要 |
A method of purifying protein farnesyltransferase (Ftase) uses recombinant technology and yeast host cells. Yeast farnesyltransferase purified by the method is useful in confirming specificity and kinetics of potential protein farnesyltransferase inhibitors. These inhibitors are useful for chemotherapy directed against cancers related to ras oncogenes.
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申请公布号 |
US5578477(A) |
申请公布日期 |
1996.11.26 |
申请号 |
US19930000931 |
申请日期 |
1993.01.05 |
申请人 |
ARCH DEVELOPMENT CORPORATION |
发明人 |
TAMANOI, FUYUHIKO |
分类号 |
A61K38/00;C12N9/10;(IPC1-7):C12N9/10;A61K38/45 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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