发明名称 |
Biocompatible, surface modified materials |
摘要 |
A method of permanently modifying the surface of a substrate material so as to develop a microscopically smooth, biocompatible surface thereon comprises covalently grafting a biocompatible polymeric material to the surface of the substrate material by radio frequency plasma-induced grafting. The biocompatible polymeric material is preferably the same as the substrate material. In addition, a method of permanently modifying the surface of a substrate material comprises subjecting the substrate surface to radio frequency plasma sufficient to raise the temperature at the substrate material to just above the glass transition temperature (Tg) of the substrate material for a time sufficient to produce a microscopically smooth, biocompatible surface on the substrate material. Further, a prosthesis used in mammals, including an intraocular lens, comprises a polymeric material core and a biocompatible polymeric material covalently grafted to the polymer core by radio frequency plasma induction.
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申请公布号 |
US5578079(A) |
申请公布日期 |
1996.11.26 |
申请号 |
US19930048036 |
申请日期 |
1993.04.14 |
申请人 |
DREXEL UNIVERSITY;OPHTHALMIC RESEARCH CORPORATION |
发明人 |
KAMEL, IHAB;SOLL, DAVID B. |
分类号 |
A61F2/00;A61F2/16;A61L27/16;A61L27/34;A61L33/00;A61L33/08;B05D3/14;B05D7/24;B29C59/14;C08J7/18;C23C8/36;(IPC1-7):A61F2/16 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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