| 发明名称 |
1H-indole-3-acetic acid hydrazide sPLA2 inhibitors |
| 摘要 |
A class of novel 1H-indole-3-acetic acid hydrazides is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids (e.g., arachidonic acid) for treatment of conditions such as septic shock.
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| 申请公布号 |
US5578634(A) |
申请公布日期 |
1996.11.26 |
| 申请号 |
US19950440154 |
申请日期 |
1995.05.12 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BACH, NICHOLAS J.;DILLARD, ROBERT D.;DRAHEIM, SUSAN E.;HERMANN, ROBERT B.;SCHEVITZ, RICHARD W. |
| 分类号 |
A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61K31/41;A61K31/425;A61K31/44;A61K31/4427;A61K31/47;A61P1/00;A61P3/04;A61P9/00;A61P11/00;A61P11/08;A61P27/16;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D209/20;C07D209/22;C07D209/24;C07D209/30;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D417/06;C07D417/12;C07F9/572;(IPC1-7):C07D209/18 |
主分类号 |
A61K31/40 |
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