摘要 |
PCT No. PCT/FR96/00555 Sec. 371 Date Oct. 31, 1997 Sec. 102(e) Date Oct. 31, 1997 PCT Filed Apr. 12, 1996 PCT Pub. No. WO96/34870 PCT Pub. Date Nov. 7, 1996Azacyloalkane derivatives of general formulahydrogen atom, an alkyl group or a phenyl group, or R1 and R2 together form an oxo group, R3 represents a hydrogen atom or an alkyl group, or alternatively R3 forms a methylene group, R4 represents an aromatic group or, when R3 forms a methylene group, R4 represents a phenylene group in which one carbon atom is linked to Y and another carbon atom, adjacent to the preceding one, is linked to the said methylene group, R5 is either a group OR7, where R7 is a hydrogen atom or a benzyl group, or an N4-methylpiperazinyl group, or alternatively a group NHR8 where R8 is a hydroxyl, pyridylmethyl or phenylmethyl group, A is an optionally substituted aromatic ring, n is equal to 1 or 2, X is CH, O or N, and Y is CH2, O or S, the process for preparing them and their applications in therapy. |