| 发明名称 |
Benzene, pyridine, naphtalene or benzophenone derivatives as inhibitors of squalene synthetase and protein farnesyltrans ferase |
| 摘要 |
The present invention provides a compound of the formula <IMAGE> which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia, atherosclerosis, or fungal infections, processes for the preparation of the compounds of the invention, intermediates useful in these processes, and pharmaceutical compositions containing the compounds. |
| 申请公布号 |
AU5673196(A) |
申请公布日期 |
1996.11.21 |
| 申请号 |
AU19960056731 |
申请日期 |
1996.05.02 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
WILLIAM R. BAKER;SAUL H. ROSENBERG;K. L. ANTHONY FUNG;TODD W. ROCKWAY;STEPHEN A. FAKHOURY;DAVID S GARVEY;B. GREGORY DONNER;STEPHEN J. O'CONNOR;RAJNANDAN N. PRASAD;WANG SHEN;DAVID M. STOUT;GERARD M. SULLIVAN |
| 分类号 |
C07C65/24;C07C65/28;C07C65/40;C07C69/94;C07C229/38;C07C233/22;C07C233/65;C07C233/69;C07C233/73;C07C233/87;C07C235/16;C07C235/34;C07C235/42;C07C235/48;C07C235/60;C07C235/84;C07C237/08;C07C237/20;C07C237/32;C07C251/48;C07C255/57;C07C259/10;C07C271/48;C07C275/42;C07C311/08;C07C311/29;C07C311/51;C07C323/59;C07C327/48;C07C333/04;C07D209/16;C07D213/40;C07D231/12;C07D271/10;C07D271/113;C07D307/88;C07D307/89;C07D309/32;C07D311/68;C07D319/06;C07D333/20 |
主分类号 |
C07C65/24 |
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