摘要 |
<p>An improved process for producing 4-hydroxy-2-pyrrolidone represented by formula (1), which is useful as an intermediate for synthesizing medicines, agricultural chemicals and so forth, by synthesizing a 4-azido-3-hydroxybutanoic ester by the reaction of a 4-halogeno-3-hydroxybutanoic ester with an alkali metal or alkaline earth metal azide followed by the catalytic reduction of the azido group of the ester and cyclization.</p> |