STABLE AQUEOUS FORMULATIONS OF 1 alpha ,25-DIHYDROXYCHOLECALCIFEROL FOR PARENTERAL ADMINISTRATION

摘要

1 alpha ,25-dihydroxycholecalciferol is a naturally occurring form of Vitamin D3. Vitamin D3 is converted to 1 alpha , 25-dihydroxycholecalciferol in the liver and kidney before it acts to stimulate intestinal calcium and phosphorous absorption. Parenteral solutions of 1 alpha , 25-dihydroxycholecalciferol are suitable for replacement therapy.