NUCLEIC ACID MOLECULE FOR TREATING B CELL MALIGNANT TUMOR, PROCESS FOR PRODUCING THE SAME AND UTILIZATION OF THE SAME

摘要

A nucleic acid molecule for treating a B cell malignant tumor which is capable of expressing a VH protein containing the part III of the complementarity-determining region (CDR) III of an immunoglobulin molecule VH specific to human B cell malignant tumor cells; a process for producing the molecules; a medicinal composition containing the molecules as the active ingredient; a protein expressed by the nucleic acid molecule; and a method for treating a B cell malignant tumor and a method for cell-mediated immune enhancement comprising the administration of the nucleic acid molecules.