发明名称 1,3,4-OXADIAZOLE-2-(3H)-ONE DERIVATIVES, PREPARATION AND USE THEREOF IN THERAPY
摘要 FIELD: medicine. SUBSTANCE: claimed invention describes 1,3,4-oxadiazol-2-(3H)-one derivatives of general formula (I):wherein Ris either hydrogen atom, or linear or branched (C) alkyl group n substituted by hydroxy group, phenoxy group, (C) alkoxy group, (C) alkylthio group, mercapto group, (C) alkoxy-(C) alkoxy group, di-((C)) alkylamino group or N- ((C) alkyl-N-propynylamino group, or is ((C)) alkynyl group, and Ris either linear or branched (C) alkyl group substituted by one or more halogen and/or hydroxy group, 1-imidazolyl group or 3-tetrahydropyranyl group, or is thi-fluoro ((C)) alkenyl group, in the form of pure enantiomers or mixture of enantiomers including recemit mixtures and also salts thereof formed from addition of pharmaceutically acceptable acids. Said compounds are used for therapeutical purposes. EFFECT: improved properties of the title compounds.
申请公布号 RU94042230(A) 申请公布日期 1996.11.20
申请号 RU19940042230 申请日期 1994.11.25
申请人 SINTELJABO 发明人 KENIG ZHAN-ZHAK;EGAM SAMIR;PJUEH FREDERIK;BJURN'E FILIPP
分类号 C07D271/10;A61K31/42;A61K31/4245;A61P25/00;A61P25/18;A61P25/24;A61P25/26;A61P25/28;C07D271/113;C07D413/12;C07D521/00 主分类号 C07D271/10
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