发明名称 3-(2-AMINOETHYL)-4-[3-(TRIFLUOROMETHYL)BENZENE]-3,4- DIHYDRO-2H-1,4-BENZOXAZINE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPY
摘要 FIELD: medicine. SUBSTANCE: claimed invention describes compounds of general formula (I):wherein Ris hydrogen, fluorine or chlorine atom or methyl, C-Calkoxy- or nitro group; Ris individually hydrogen atom or C-Calkyl group; Ris individually 2,3-dihydro-1H-inden-2-yl group, 2,3-dihydro-1H-inden-1-yl group or 1,2,3,4- tetrahydronaphthalen-1-yl group, or alternatively Rand Rtogether with nitrogen atom to which they are attached form 1,2,3,4-tetrahydro-9H-pyrido [3,4-b] indol- 2-yl group, 1,2,3,4-tetrahydro-9H-pyrido [4,3-b] indol-3- yl group, 4,5,6,7-tetrahydrothieno [2,3-c] pyrid-6-yl group, 4,5,6,7-tetrahydrothieno [3,2-c] pyrid-6-yl group or 2,3-dihydro-1,4-isoindol-2-yl group. EFFECT: improved properties of the title compounds.
申请公布号 RU95101386(A) 申请公布日期 1996.11.20
申请号 RU19950101386 申请日期 1995.02.02
申请人 SINTELJABO 发明人 ZHORZH PASKAL';FROST DZHONATAN;PASO PATRIK;RUSSEL' KORINN;BARCH REZHIN;VIL'JAMS POL KHAUARD;MJULLER ZHAN-KLOD
分类号 C07D265/26;A61K31/38;A61K31/395;A61K31/435;A61K31/535;A61K31/538;A61P9/10;A61P25/00;A61P25/28;A61P27/02;C07D265/36;C07D413/06;C07D471/04;C07D495/04 主分类号 C07D265/26
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