发明名称 |
Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts and the chemical compound 2-fluorocyclopropylisocyanate |
摘要 |
The prodn. of 2-fluorocyclopropylamine sulphonic acid salts (A) comprises (a) converting 2-fluorocyclopropane-carboxylic acid (B) into the acid chloride or bromide, (b) reacting with an azide in presence of a solvent to form 2-fluoropropyl-isocyanate (C) and (c) hydrolysis with water in presence of a sulphonic acid. Also claimed are 2-fluorocyclopropyl isocyanate, (1S,2R)- and (1R,2S)- 2-fluorocyclopropyl isocyanate, and mixts. of the (1S,2R)- and (1R,2S)-2-fluorocyclopropyl isocyanate cpds. |
申请公布号 |
EP0743299(A1) |
申请公布日期 |
1996.11.20 |
申请号 |
EP19960106952 |
申请日期 |
1996.05.03 |
申请人 |
BAYER AG |
发明人 |
LUI, NORBERT, DR.;MARHOLD, ALBRECHT, DR. |
分类号 |
C07C265/08;C07C209/62;C07C265/10;C07C303/32;C07C309/25;C07C309/30 |
主分类号 |
C07C265/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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