| 摘要 |
PURPOSE: To produce a glyoxylic acid ester compound useful as a synthetic raw material for a medicine, an agrochemical, etc., at a low cost by using an aldehyde derivative, which is easily available and less expensive, as a raw material. CONSTITUTION: This compound of formula II (e.g. methyl glyoxylate) is produced by oxidizing an aldehyde derivative of formula I (R is an alkyl, an aryl or an alkoxyalkyl) (e.g. methoxyacetoaldehyde) with (B) molecular oxygen (e.g. the usage of the oxygen is 0.5-5 times molar quantity against the mol number of the component A) in a gaseous phase. Preferably further, the reaction is carried out in the presence of a solid catalyst, and the preparation of the catalyst is carried out e.g. by dissolving a water-soluble metal salt of the constituting metal such as vanadium in water, impregnating the aqueous solution on a carrier such as alumina, drying this and subsequently baking at 200-600 deg.C in an inert gas. |
