| 发明名称 |
Bis (biaryl) compounds as inhibitors of leukotriene biosynthesis |
| 摘要 |
Compounds having the Formula I: Ar1Ar2XAr3Ar4 I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
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| 申请公布号 |
US5576338(A) |
申请公布日期 |
1996.11.19 |
| 申请号 |
US19950388787 |
申请日期 |
1995.02.15 |
| 申请人 |
MERCK FROSST CANADA, INC. |
发明人 |
FRIESEN, RICHARD;DUCHARME, YVES;DUBE', DANIEL;LEPINE, CAROLE;DELORME, DANIEL;HAMEL, PIERRE |
| 分类号 |
C07D217/04;C07D311/16;C07D405/04;C07D405/14;C07D407/04;C07D409/14;C07D413/04;C07D417/14;(IPC1-7):A61K31/44;C07C311/02;C07D401/04 |
主分类号 |
C07D217/04 |
| 代理机构 |
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