发明名称 |
Sustained-release multi-granule tablet |
摘要 |
A sustained-release multi-granule tablet is obtained by compressing sustained-release granules, which contains an active substance, and a formulation adjuvant. Each of the granules has been coated in advance with a layer of the formulation adjuvant and/or a layer of a mixture of the formulation adjuvant and the active substance. The tablet releases an active substance at a suitable velocity into the digestion tract, resulting in that the variability in the absorption of the drug in each patient and among individual patients is minimized to achieve maximum bioavailability.
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申请公布号 |
US5576021(A) |
申请公布日期 |
1996.11.19 |
申请号 |
US19940275240 |
申请日期 |
1994.07.15 |
申请人 |
EISAI CO., LTD. |
发明人 |
ANDOH, HIDENOBU;WATANABE, SUMIO;MIYAKE, YASUO |
分类号 |
A61K9/20;A61K9/22;A61K9/26;A61K31/551;(IPC1-7):A61K9/22 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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