摘要 |
<p>Propenone derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, wherein R1 represents hydrogen or lower alkyl; R?2 and R3¿ are the same or different and each represents hydrogen, lower alkyl or optionally susbtituted aralkyl, or R?2 and R3¿ form together optionally substituted methylene or ethylene; R4 represents hydrogen, hydroxy, lower alkyl, optionally substituted aralkyl, lower alkoxy, optionally substituted aralkyloxy or halogeno; and X represents optionally substituted indolyl, provided that when OR3 is located at the 2- or 6-position of the benzene ring, then R3 is not hydrogen, while when R4 is located at the 2- or 6-position of the benzene ring, then R4 is not hydroxy, and the case where OR?2, OR3 and R4¿ represent together 3,4-dimethoxy or 3,4,5-trimethoxy is excepted.</p> |