发明名称 LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONELOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES SECRETAGOGUES
摘要 The present invention comprises growth hormone releasing peptides/peptidomimetics (GHRP) capable of causing release of growth hormone from the pituitary. Compositions containing the GHRP's of this invention are used to promote growth in mammals either alone or in combination with other growth promoting compounds, especially IGF-1. In a method of this invention GHRP's in combination with IGF-1 are used to treat Type II diabetes. An exemplary compound of this invention is provided below. <CHEM> <IMAGE>
申请公布号 WO9615148(A3) 申请公布日期 1996.11.14
申请号 WO1995US14968 申请日期 1995.11.16
申请人 GENENTECH INC 发明人 SOMERS TODD C;ELIAS KATHLEEN A;CLARK ROSS G;MCDOWELL ROBERT S;STANLEY MARK S;BURNIER JOHN P;RAWSON THOMAS E
分类号 C07D295/12;A61K31/40;A61K31/403;A61K31/404;A61K31/4427;A61K31/445;A61K31/4465;A61K31/495;A61K31/535;A61K31/5375;A61K38/00;A61K38/04;A61K38/27;A61P3/08;A61P5/00;C07D209/16;C07D209/20;C07D211/62;C07D401/12;C07D403/12;C07K5/02;C07K5/023;C07K5/027;C07K5/03;C07K5/065;C07K5/078;C07K5/087;C07K5/097;C07K5/107;C07K5/117;C07K7/06;C07K14/60 主分类号 C07D295/12
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