发明名称 Cyclic amide derivatives
摘要 <p>Disclosed is a cyclic amide derivative having the formula (I) or a salt thereof: R&lt;1&gt;-(CH2)n-Z in which R&lt;1&gt; is a group derived from a cyclic amide compound, substituted or unsubstituted, n is zero or an integer of 1 to 10 and Z is &lt;CHEM&gt; R&lt;2&gt; being an aryl, a substituted aryl, a cycloalkyl or a heterocyclic group, m being an integer of 1 to 6, provided that this compound is not one of the following list or a salt thereof: 3-(1-Benzyl-4-piperidyl)-1,2,3,4-tetrahydro-1H-quinazolin-2-on 3-Ä2-(1-Benzyl-4-piperidyl)ethylÜ-1,2,3,4-tetrahydro-1H-quinazolin-2-on 3-Ä2-(1-Benzyl-4-piperidyl)ethylÜ-1,2,3,4-tetrahydro-1H-quinazolin-2,4 -dion 3-Ä2-(1-Benzyl-4-piperidyl)ethylÜ-7-chloro-1,2,3,4-tetrahydro-1H-quina zolin-2,4,-dion 3-Ä2-(1-Benzyl-4-piperidyl)ethylÜ-6-methyl-1,2,3,4-tetrahydro-1H-quina zolin-2,4-dion 3-Ä3-(1-Benzyl-4-piperidyl)propylÜ-1,2,3,4-tetrahydro-1H-quinazolin-2, 4-dion. The cyclic amide compound is pharmacologically effective to prevent and treat diseases due to insufficiency of the central choline functions.</p>
申请公布号 EP0742216(A2) 申请公布日期 1996.11.13
申请号 EP19960109320 申请日期 1991.06.13
申请人 EISAI CO., LTD. 发明人 SUGIMOTO, HACHIRO;YONAGA, MASAHIRO,;KARIBE, NORIO;IIMURA, YOUICHI;NAGATO, SATOSHI;SASAKI, ATSUSHI;YAMANISHI, YOSHIHARU;OGURA, HIROO;KOSASA, TAKASHI;UCHIKOSHI, KUMI;YAMATSU, KIYOMI
分类号 A61K31/40;A61K31/00;A61K31/395;A61K31/42;A61K31/423;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/454;A61K31/495;A61K31/496;A61K31/4985;A61K31/505;A61K31/517;A61K31/519;A61K31/535;A61K31/536;A61K31/5365;A61K31/5377;A61K31/55;A61P9/00;A61P25/00;A61P25/02;A61P25/28;A61P43/00;C07D207/16;C07D263/58;C07D265/18;C07D265/26;C07D401/04;C07D401/06;C07D401/14;C07D405/14;C07D409/14;C07D413/06;C07D413/12;C07D413/14;C07D471/04;C07D475/02;C07D487/04;C07D495/04;C07D498/04;C12N9/99;(IPC1-7):C07D401/04;C07D407/14;A61K31/16 主分类号 A61K31/40
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