发明名称 SPHINGOMYELIN DERIVED FROM RERYTHROCYTE AS RAW MATERIAL, NEW PRODUCTION OF CERAMIDE AND TREATING AGENT OR COSMETIC IN WHICH CERAMIDE IS BLENDED
摘要 PURPOSE: To inexpensively obtain ceramide for a humectant component, etc., of skin in large amount by carrying out hydrolysis or enzymatic decomposition of erythrocyte or the residue after producing hemoglobins from the erythrocyte or sphingomyelin lipids extracted from the erythrocyte. CONSTITUTION: Erythrocyte, the residue generated when hemoglobins are produced from the erythrocyte or spingolipids (e.g. sphingomyelin) obtained by extracting the erythrocyte is hydrolyzed using a strong acid or is subjected to enzymatic decomposition using an immobilized enzyme, etc., obtained by immobilizing a crude enzyme obtained by extracting with dichloromethane, etc., from a cultured solution of Bacillus cereus (IAM1208) to inexpensively provide the objected ceramide useful as a humectant of skin, a treating agent for chapped skin, fine wrinkles, atopic dermatitis or as a cosmetic in large amounts.
申请公布号 JPH08294395(A) 申请公布日期 1996.11.12
申请号 JP19950134332 申请日期 1995.05.31
申请人 YAKURIGAKU CHUO KENKYUSHO:KK 发明人 TAKAHASHI HIDEHIKO;HARA SUSUMU;TOMITANI YUMIKO
分类号 A61K8/00;A61K8/30;A61K8/42;A61K8/44;A61K8/63;A61K8/68;A61K31/16;A61K31/164;A61K35/18;A61P17/00;A61Q19/00;C12P13/02;C12R1/085;(IPC1-7):C12P13/02;A61K7/00 主分类号 A61K8/00
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