发明名称 Method of lowering cholesterol
摘要 A method of lowering cholesterol which comprises administering to a host requiring such treatment an effective amount of a compound of the formula <IMAGE> I wherein one of R1 and R2 is C1-7-alkyl and the other is C1-7-alkyl or C2-6-alkenyl-methyl; L is C1-11-alkylene or C2-11-alkenylene optionally bonded to the phenyl group via an O atom or L is 1,4-phenylene; n is 0 or, when L contains an O atom, n is 0 or 1; Q is C1-7-alkyl, C2-10alkenyl or a group of formula <IMAGE> Q' wherein R is H, halogen, CF3, CN or NO2; R3 and R4 are H, C1-4-alkyl or halogen; and R5 is H or, when R is H, R5 is H or halogen; or a pharmaceutically acceptable acid addition salt thereof, as well as certain compounds of formula I, are described.
申请公布号 US5574071(A) 申请公布日期 1996.11.12
申请号 US19950468114 申请日期 1995.06.06
申请人 HOFFMANN-LA ROCHE INC. 发明人 AEBI, JOHANNES;GUERRY, PHILIPE;JOLIDON, SYN+E,ACU E+EE SE;MORAND, OLIVIER
分类号 A61K31/24;A61K31/135;A61K31/137;A61K31/138;A61K31/277;A61P3/06;A61P9/10;C07C211/26;C07C217/18;C07C217/20;C07C217/22;C07C217/46;C07C225/08;C07C225/14;C07C225/16;C07C225/22;C07C255/56;(IPC1-7):A61K31/135 主分类号 A61K31/24
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