发明名称 Nanoparticulate diagnostic mixed carboxylic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging
摘要 This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen, and/or lymph system of a mammal comprising administering a contrast effective amount of a mixed carbonic anhydride as a contrast agent having the structure kyl R2 is COR3 R3 is H, alkyl or aryl Y is NR1R2 or CONR1R3 and Z is alkyl, aryl or aralkyl. This invention further relates to novel mixed carboxylic anhydride contrast agents having the above structure to x-ray contrast compositions comprising such agents, and to methods of x-ray diagnostic imaging utilizing such agents.
申请公布号 US5573749(A) 申请公布日期 1996.11.12
申请号 US19950401397 申请日期 1995.03.09
申请人 NANO SYSTEMS L.L.C. 发明人 ILLIG, CARL R.
分类号 C07C233/54;C07J41/00;(IPC1-7):A61K49/04;C07C69/96;C07C63/68 主分类号 C07C233/54
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