发明名称 Process for purifying echinocandin B deacylase
摘要 Echinocandin B deacylase is purified to near homogeneity from Actinoplanes utahensis by a process comprising, in order, extracting the soluble enzyme, heating to 60 DEG C., hydrophobic interaction chromatography, (NH4)2SO4 fractionation, gel filtration, cation exchange chromatography, dye-ligand chromatography, gel filtration, and cation-exchange chromatography.
申请公布号 US5573936(A) 申请公布日期 1996.11.12
申请号 US19950444126 申请日期 1995.05.18
申请人 ELI LILLY AND COMPANY 发明人 KREUZMAN, ADAM J.;YEH, WU-KUANG
分类号 C07K7/08;C07K7/56;C12N9/80;C12P21/02;C12P21/04;C12R1/01;(IPC1-7):C12N9/16 主分类号 C07K7/08
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