N-aminoalkyl-substituted nitrogen-containing five membered heterocyclic compounds

摘要

Disclosed are new alkylenediamine derivatives of the following formula which are effective for treatment of dysuria are disclosed: <IMAGE> <IMAGE> wherein R1 is hydrogen, alkyl, or a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group; R2 is a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group; R3 and R4 represent hydrogen, alkyl, aralkyl or aryl; or R3 and R4 are combined to form one of substituted or unsubstituted 5- to 7-membered heterocyclic groups; X is oxygen, sulfur or imino; Y is oxygen or sulfur; Z is -CH2-, -CO- or -CS-; m is an integer of 0-4; n is an integer of 0-4; r is 0 or 1; and p and q represent an integer of 0-5 provided that p plus q is 1-5.