MONOCLONAL ANTIBODY REACTIVE WITH HUMAN-ORIGIN CETP AND METHOD OF QUANTIFYING HUMAN-ORIGIN CETP

摘要

A monoclonal antiboy that has a highly specific avidity with human-origin CETP (CETP inhibitory activity) and that is useful as a reagent for quantifying and purifying human-origin CETP and as a preventive or remedy for hyperlipemia and arteriosclerosis; and methods of quantifying and purifying human-origin CETP. The antibody permits the human-origin CETP contained in a sample to be quantified readily with a high sensitivity without the necessity for treating the sample with heat or surfactants. As the antibody has such a high CETP inhibitory activity, it is useful as medicines for treating or preventing various diseases such as hyperlipemia, hyper-high-density-lipoproteinemia, hypercholesterolemia, and arteriosclerosis.