An isolated nucleic acid molecule encoding a variant hK2 polypeptide is provided. Further provided is an isolated, purified variant hK2 polypeptide useful in preparing immunogenic compositions and vaccines. Methods of employing the nucleic acid molecule or polypeptide of the invention are also provided.
申请公布号
CA2219876(A1)
申请公布日期
1996.11.07
申请号
CA19962219876
申请日期
1996.05.02
申请人
HYBRITECH INCORPORATED;MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人
SAEDI, MOHAMMAD S.;KUUS-REICHEL, KRISTINE;ROCHE, PATRICK C.;TINDALL, DONALD J.;KUMAR, ABHAY;MIKOLAJCZYK, STEPHEN D.;BOSTWICK, DAVID G.