发明名称 |
METHOD FOR INTRODUCING AND EXPRESSING GENES IN ANIMAL CELLS |
摘要 |
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, a therapeutica agent, and immunoregulatory agent or an anti-sense RNA or a catalytic RNA.
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申请公布号 |
WO9634631(A1) |
申请公布日期 |
1996.11.07 |
申请号 |
WO1996US05326 |
申请日期 |
1996.04.24 |
申请人 |
UNIVERSITY OF MARYLAND AT BALTIMORE |
发明人 |
POWELL, ROBERT, J.;LEWIS, GEORGE, K.;HONE, DAVID, M. |
分类号 |
C12N15/09;A61K35/74;A61K39/00;A61K45/00;A61K48/00;A61P31/04;A61P31/12;A61P33/00;C12N1/21;C12N5/10;C12N15/87;(IPC1-7):A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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