Increasing immune response to tumour cells by increasing expression of TAP or LMP proteins
摘要
Immune response to a tumour cell is increased by introducing into the cells nucleic acid (I) encoding TAP and/or LMP proteins, then expressing it to increase the intracellular concn. of these proteins. Also new are: (1) a method for detecting tumour antigens (TAg); (2) tumour cells contg. (I); and (3) a method for producing cytotoxic T lymphocytes (CTL) against autologous tumour cells.
申请公布号
DE19516040(A1)
申请公布日期
1996.11.07
申请号
DE19951016040
申请日期
1995.05.04
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH, 55218 INGELHEIM, DE
发明人
SELIGER, BARBARA, 55131 MAINZ, DE;HUBER, CHRISTOPH, 55131 MAINZ, DE
