发明名称 |
SUBSTITUTED BENZHYDRYLAMINES AS HANDLES FOR SOLID PHASE PEPTIDE SYNTHESIS |
摘要 |
<p>PCT No. PCT/US92/02962 Sec. 371 Date Jul. 5, 1994 Sec. 102(e) Date Jul. 5, 1994 PCT Filed Apr. 10, 1992 PCT Pub. No. WO92/18144 PCT Pub. Date Oct. 29, 1992The present invention is directed to a novel "handle" for solid phase peptide synthesis. The handles can be converted from a stable form to a labile form, allowing for cleavage of a peptide amide from the support after synthesis under mild conditions, and after deprotection of the amino acid side chains. The handles are based on a substituted benzhydrylamine skeleton.</p> |
申请公布号 |
GR3020463(T3) |
申请公布日期 |
1996.10.31 |
申请号 |
GR19960401664T |
申请日期 |
1996.07.04 |
申请人 |
LEBL, MICHAL;PATEK, MARCEL |
发明人 |
LEBL, MICHAL;PATEK, MARCEL |
分类号 |
C07C317/32;C07C317/40;C07C323/32;C07C323/41;C07K1/04;C07K1/113;C07K7/06;C07K7/16;(IPC1-7):A61K38/00;C07C261/00 |
主分类号 |
C07C317/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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