| 摘要 |
<p>The invention concerns derivatives of the formula (I), wherein n is 1, 2 or 3 and each R2 is independently halogeno; and R1 is amino-(2-4C)alkylamino, (1-4C)alkylamino-(2-4C)alkylamino, di-[(1-4C)alkyl]amino-(2-4C)alkylamino, pyrrolidin-1-yl-(2-4C)alkylamino, piperidino-(2-4C)alkylamino, morpholino-(2-4C)alkylamino, piperazin-1-yl-(2-4C)alkylamino or 4-(1-4C)alkylpiperazin-1-yl-(2-4C)alkylamino; or pharmaceutically acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them, and the use of the receptor tyrosine kinase inhibitory properties of the compounds in the treatment of proliferative disease such as cancer.</p> |
