DELETIONSMUTANTEN VON BOVINEM HERPUVIRUS-1, AUF DIESE BASIERTE IMPFSTOFFE,DIAGNOSESÄTZE FÜR DEN NACHWEIS VON BOVINEM HERPESVIRUS-1

摘要

PCT No. PCT/NL92/00097 Sec. 371 Date Jan. 21, 1994 Sec. 102(e) Date Jan. 21, 1994 PCT Filed Jun. 5, 1992 PCT Pub. No. WO92/21751 PCT Pub. Date Dec. 10, 1992A deletion mutant of bovine herpesvirus type 1 which has a deletion in the glycoprotein gE-gene and which may further have a deletion in the thymidine kinase gene and/or the glycoprotein gI-gene, or have an insertion of a heterologous gene is disclosed. Recombinant nucleic acids which encode the gE-gene or a part thereof are also disclosed, in addition to vaccines and a method of treatment.