发明名称 |
MULTIMERIC, RECOMBINANT UREASE VACCINE |
摘要 |
Methods and compositions are provided for preventing and/or treating Helicobacter (e.g., H. pylori) infection. The compositions of the invention, which are used in the methods of the invention (which include mucosal administration of the compositions), include compositions containing multimeric complexes of recombinant, enzymatically inactive Helicobacter urease in a pharmaceutically acceptable carrier or diluent; and compositions containing (a) a Helicobacter antigen, and (b) an antibiotic, an antisecretory agent, a bismuth salt, or a combination thereof. |
申请公布号 |
CA2219201(A1) |
申请公布日期 |
1996.10.31 |
申请号 |
CA19962219201 |
申请日期 |
1996.04.25 |
申请人 |
ORAVAX, INC. |
发明人 |
THOMAS, WILLIAM D., JR.;ACKERMAN, SAMUEL K.;SUSSMAN, ILENE;ERMAK, THOMAS;PAPPO, JACQUES;KLEANTHOUS, HAROLD;MONATH, THOMAS P.;LEE, CYNTHIA K.;BHAGAT, HITESH;WELTZIN, RICHARD A.;SOMAN, GOPALAN;GUIRAKHOO, FARSHAD |
分类号 |
A61K51/00;A61K31/34;A61K31/415;A61K31/425;A61K31/557;A61K31/70;A61K38/46;A61K39/02;A61K39/39;A61K45/00;A61P1/00;A61P1/04;C12N9/14;C12N9/80 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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