发明名称 N-(Pyrrolo(2-3-d)pyrimidin-3-ylacyl)-Glutaminsäurederivate
摘要 <p>N-(Acyl)glutamic acid derivatives in which the acyl group is substituted with 4-hydroxypyrrolo[2,3-d]pyrimidin-3-yl group are antineoplastic agents. A typical embodiment is N-[4-(2-{4-hydroxy-6-aminopyrrolo[2,3-d]pyrimidin-3-yl}-ethyl)benzoyl] -L-glutamic acid.</p>
申请公布号 DE69025723(T2) 申请公布日期 1996.10.31
申请号 DE1990625723T 申请日期 1990.12.10
申请人 THE TRUSTEES OF PRINCETON UNIVERSITY, PRINCETON, N.J., US;ELI LILLY AND CO., INDIANAPOLIS, IND., US 发明人 TAYLOR, EDWARD C., PRINCETON, NEW JERSEY 08544, US;KUHNT, DIETMAR G., W-5090 LEVERKUSEN 1, DE;SHIH, CHUAN, INDIANAPOLIS, INDIANA 46256, US;GRINDEY, GERALD B., INDIANAPOLIS, INDIANA 46502, US
分类号 C07D487/04;A61K31/195;A61K31/505;A61K31/519;A61P35/00;A61P35/02;A61P43/00;(IPC1-7):C07D487/04 主分类号 C07D487/04
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