Aryl glycinamide derivatives, methods of producing these sub stances and pharmaceutical compositions containing such comp ounds

摘要

The invention relates to new arylglycinamide derivatives of general formula Iand the pharmaceutically acceptable salts thereof, whereinR1 and R2 together with the N to which they are bound form a ring of the formula whereinp is 2 or 3 andX denotes oxygen, N(CH2)nR6 or CR7R8,and R3, R4, R5, R6, R7, R8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.