发明名称 NITROGENOUS ESTERIC DERIVATE OF THEOPHYLLIN-8-P-NITROGENOUSPHENACYLHYDRAZONE AND PREPARATION PROCESS THEREFOR
摘要 The invention relates to N-(2-hydroxyethyl)-p-nitrogenousphenacyl-8-theophyllinehydrazone, as well as to a process for preparing the same. The process consists in reacting -bromine-p-nitrogenouspneacyl-8-theopyllinehydrazone with nitrogenous monoethanole amine nitrate in dimethylformamide medium, in the presence of anhydrous potassium carbonate. The derivative is a heavy brown-coloured compound with a melting point of 172...174 degree C, soluble in organic solvents, non-soluble in water, with antihipertensive and coronary-dillating properties
申请公布号 RO111461(B1) 申请公布日期 1996.10.30
申请号 RO19900143911 申请日期 1990.01.25
申请人 INSTITUTUL DE MEDICINA SI FARMACIE 发明人 DANILA GHEORGHE;UNGUREANU MARGARETA
分类号 C07D473/08 主分类号 C07D473/08
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