摘要 |
The invention concerns an anhydrous transdermal preparation comprising in a 20-100% lyotropic liquid crystalline arrangement: 5-15 w.% of optically active or racemic N-methyl-N-(phenyl-2-propyl)-2-propynylamine or N-methyl-N-(1-(4-fluoro-phenyl)-2-propyl)-2-propynylamine or their therapeutically acceptable salts, 40-70 w.% of liquid polyoxyethyleneglycol, 10-20 w.% of solid polyoxyethyleneglycol, 2-30 w.% of a nonionic surface active agent, 2-20 w.% of propyleneglycol, if desired 0.5-2 w.% of a polymer the a value of which is > 0.6, and if desired other auxiliary agents. |
申请人 |
CHINOIN GYOGYSZERES VEGYESZETI TERMEKEK GYARA RT |
发明人 |
SZABO, ANNA, Z.;SZABO NEE UJHELYI GABRIELLA;TOTH, ANTAL, DR.;SZUTS, TAMAS, DR.;MAGYAR, KALMAN, DR.;LENGYEL, JOZSEF, DR.;PINTER, JANOS, DR.;SZEKELY, ANNA, DR.;SZEGO, ANDRAS, DR.;MARMAROSI NEE KELLNER KATALIN |