| 摘要 |
The present invention provides a method for treating or preventing certain metabolic disorders comprising the administration of 3-guanidinopropionic acid (3-GPA). These metabolic disorders of human and animal metabolism, e.g hyperglycemia, impaired glucose tolerance, hyperinsulinemia and insulin insensitivity, hyperamylinemia, excess adiposity, and hyperlipidemia, may occur in the following disease states: non-insulin dependent diabetes mellitus (NIDDM), obesity, hypertension and atherosclerosis. 3-GPA may be administered admixed in the diet of farm animals or as a pharmaceutical preparation such as an oral tablet or capsule, by injection, or by implantable sustaind release devices thereby increasing the protein content of the carcass while decreasing its fat content. This would produce muscle tissue with less fat.
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