SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS

摘要

The present invention relates to the use of substituted dihydrobenzofuran derivatives having 5-HT4 receptor agonist activity, which act as therapeutic prokinetic agents in treatment of gastrointestinal disorders such as, e.g., dyspepsia, gastro-oesophageal reflux disease (GORD) or gastroparesis. The compounds of the invention can also be useful in the treatment of CNS disorders, characterized by learning and/or memory dysfunctions. Several of these substituted dihydrobenzofuran derivatives are novel compounds and, as such, constitute a further object of the invention, together with the process for their preparation and the pharmaceutical compositions containing them.